Aminosaccharide contrast agents for magnetic resonance images

Details Aminosaccharide contrast agents for magnetic resonance images Aminosaccharide contrast agents for magnetic resonance images

1992-11-12

1994-07-19

Hollinden, Gary E.

Drug, bio-affecting and body treating compositions

In vivo diagnosis or in vivo testing

Magnetic imaging agent

436173, 436806, 1286534, 536 291, 534 16, 514184, 514492, 514502, 514836, 556 50, 556 63, 556107, 556117, 556134, 556148, A61B 5055, C07H 1512

Patent

active

053307437

ABSTRACT:
A contrast enhancing agent for magnetic resonance images having a chelating agent, which can be bound to metals having at least one unpaired electron. Examples of such chelating agents include 3,6,9-tris(carboxymethyl)-1, 11-bis(dimethylamine)-3,6,9-triazaundecane; 3,6,9-tris(carboxymethyl)-1, 11-bis(diethanolamino) 3,6,9-triazaundecane; 3,6,9-tris(carboxymethyl)-1, 11-bis(tris(hydroymethyl) aminomethane)-3,6,9-triazaundecane; 3,6-bis(carboxymethyl-1,8-bis(N-carboxymethylglucosamino)-3,6-diazoctane; DTPA-bis(galactosamide), DTPA-Bis(glucosamide), DTPA-Bis(pyridoxamide), and poly-(DTPA-ethylenediamide).

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