Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...
Reexamination Certificate
2009-05-19
2011-11-01
Seaman, D M (Department: 1625)
Organic compounds -- part of the class 532-570 series
Organic compounds
Heterocyclic carbon compounds containing a hetero ring...
C514S312000
Reexamination Certificate
active
08049014
ABSTRACT:
Provided are a novel aminoquinoline compound represented by Formula 1 or a pharmaceutically acceptable salt thereof, preparation method thereof, and a pharmaceutical composition for preventing or treating cutaneous cancer, comprising the aminoquinoline compound or pharmaceutically acceptable salt thereof. Since the compound of Formula 1 exhibits excellent anti-proliferative effect on melanoma tumor cells, it is useful for preventing or treating cutaneous cancer.wherein R1, R2, and R3are defined in the specification.
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Office Action issued by the Korean Patent Office on Feb. 1, 2011 in connection with corresponding Korean Patent Application No. 10-2009-00025560.
Scott M. Wilhelm et al., “Bay 43-9006 Exhibits Broad Spectrum Oral Antitumor Activity and Targets the RAF/MEK/ERK Pathway and Receptor Tyrosine Kinases Involved in Tumor Progression and Angiogenesis,” Cancer Research 64, 7099-7109, Oct. 1, 2004.
Cho Seung-Joo
Hah Jung-Mi
Kim Dong-Jin
Lee So-Ha
Nam Bong-Soo
Korea Institute of Science and Technology
Ostrolenk Faber LLP
Seaman D M
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