Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...
Patent
1976-03-03
1977-08-23
Coughlan, Jr., Paul M.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Bacterium or component thereof or substance produced by said...
A61K 31505
Patent
active
040441369
ABSTRACT:
A series of novel 2-amino and 4-aminoquinazoline derivatives have been prepared, including their acid addition salts. These derivatives all possess a single nitrogen-containing benzo-fused heterocyclic ring moiety at either the 4- or 2-positions of the molecule, respectively, with the ring moiety being attached through the nitrogen atom to the aforesaid quinazoline nucleus. Such compounds are useful in therapy as highly potent antihypertensive agents. Methods for their preparation are described in detail, including various synthetic routes leading to the required novel intermediates.
REFERENCES:
patent: 3635979 (1972-01-01), Hess
patent: 3960861 (1976-06-01), Danilewicz et al.
Danilewicz John Christopher
Kemp John Edward Glyn
Wright James Robert
Coughlan, Jr. Paul M.
Pfizer Inc.
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