Aminopyrimidine derivatives as PLK1 inhibitors

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

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C514S275000, C544S295000, C544S324000

Reexamination Certificate

active

07977336

ABSTRACT:
The present invention relates to a compound represented by Formula [I]:or a pharmaceutically acceptable salt or ester thereof, wherein R1and R2, which may be the same or different, are each a hydrogen atom, a lower alkyl group, a cycloalkyl group, or the like; R3and R4, which may be the same or different, are each a hydrogen atom, a lower alkyl group, NRaRb, a phenyl group, a lower alkyl group substituted with a phenyl group, a 4-to 7-membered aliphatic heterocyclic group, a lower alkyl group substituted with a 4- to 7-membered aliphatic heterocyclic group, a 5-or 6-membered aromatic heterocyclic group, a lower alkyl group substituted with a 5-or 6-membered aromatic heterocyclic group, or the like; and R5is a hydrogen atom, a cyano group, a halogen atom, or a lower alkyl group.

REFERENCES:
patent: 2577947 (2006-03-01), None
patent: 1790650 (2007-05-01), None
patent: 2006/502164 (2006-01-01), None
patent: 03/000682 (2003-01-01), None
patent: 2004/043936 (2004-05-01), None
patent: WO2005/092899 (2005-10-01), None
Simone, Cecil Textbook of Medicine, 20thEdition, vol. 1, pp. 1004-1010, 1996.
Feng, D et al., Bioorganic & Medicinal Chemistry Letters, vol. 16, pp. 5978-5982 (2006), “Synthesis and SAR of 2-(4-fluorophenyl)-3-pyrimidin-4-ylimidazo[1,2-alpha]pyridine derivatives as anticoccidial agents”.

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