Aminopyrimidine derivatives as antiviral agents for respiratory

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

A61K 31505

Patent

active

052566684

ABSTRACT:
Antiviral activity against respiratory syncytial virus has been found in some substituted 6-aminopyrimidines having the formula: ##STR1## wherein R.sup.1 is lower alkyl, preferably methyl or t-butyl, R.sup.2 is halogen or cyano, and R.sup.3 is C.sub.1 -C.sub.6 alkyl or --(CH.sub.2).sub.n R.sup.4 where n is 1 or 2 and R.sup.4 is phenyl, phenyl substituted by lower alkoxy, lower alkyleneoxy, bromo, or 3,4-methylenedioxy; 3 or 4-pyridinyl, pyridinyl substituted by cyano or bromo, thienyl, or di-(C.sub.1 -C.sub.6 alkyl)amino.

REFERENCES:
patent: 4505910 (1985-03-01), Bagli
patent: 4617393 (1986-10-01), Bagli et al.
patent: 4980355 (1990-12-01), Zondler et al.
patent: 5002949 (1991-03-01), Peseckis et al.
Belshe and Hay, J. Respiratory Diseases 10:552-561 (1989).
Bagli et al., J. Med. Chem. 31, 814-823 (1988).

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Aminopyrimidine derivatives as antiviral agents for respiratory does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Aminopyrimidine derivatives as antiviral agents for respiratory , we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Aminopyrimidine derivatives as antiviral agents for respiratory will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-959604

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.