Aminopyridine derivatives as mGluR5 antagonists

Details Aminopyridine derivatives as mGluR5 antagonists Aminopyridine derivatives as mGluR5 antagonists

2007-04-17

2007-04-17

McKenzie, Thomas (Department: 1625)

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C546S304000, C546S312000, C514S333000, C514S357000

Reexamination Certificate

active

11225490

ABSTRACT:
The invention relates to novel aminopyridine derivatives of formula (I) wherein R1is methyl an R4and amino group —NR6R7and R5forms an arylalkynyl- or heteroarylalkynyl-group. The compounds are useful in the prevention or treatment of central nervous system disorders as well as other disorders modulated by mGluR5 receptors

REFERENCES:
patent: 6187777 (2001-02-01), Norman et al.
patent: WO-99/02497 (1999-01-01), None
Jeong et. al., “Assembly and Binding Properties of Osmate Ester-Bridged Binuclear Macrocycles”, J. Org. Chem. 1999, 64, 9459-9466.

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