Aminopyridine derivatives as estrogen receptor modulators

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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C514S318000, C514S340000, C546S208000, C546S257000

Reexamination Certificate

active

10473087

ABSTRACT:
Aminopyridine derivatives of the following formula I which exhibit pharmacological activity at estrogen receptors alpha (ERα) and beta (ERβ) are described herein. The described invention also includes compositions and medicaments containing the aminopyridine derivatives as well as processes for the preparation and use of such compounds, compositions and medicaments.

REFERENCES:
patent: 99/32447 (1999-07-01), None
patent: 02/22601 (2002-03-01), None
Katritsky, et al “Synthesis of 2-alkylamino- and 2-dialkylamino-4,6-diarylpyridines and 2,4,6-trisubstituted pyrimidines using solid-phase bound chalcones,” J. Comb. Chem, 2000, vol. 2, No. 2, pp. 182-185.
Katritsky et al, “Benzotriazole-assisted preparations of 2-(sunstituted amino) pyridines and pyrid-2-ones,” J. Org. Chem, 1997, vol. 62, No. 18, pp. 6210-6214.
CAPLUS Accession No. 1991:429240, abstract of Shaihla, V et al, “Synthesis and antibacterial activity of some new fluorinated pyrido[2,3-d] pyrimidine derivatives,” Ind. J. Pharm. Sciences, 1990, vol. 52, No. 1, pp. 13-15.
Katritzki, A.R. et al., “Synthese of 2-alkylamino-and 2-dialkylamino-4,6-diarylpyridines and 2,4,6-trisubstituted Pyrimidines Using Solid-Phase Bound Chalcones,”Journal of Combinatorial Chemistry, vol. 2, No. 2, Feb. 26, 2000, pp. 182-185.
Henke, B.R., et al., “2-Amino-4,6-Diarylpyridines as Novel Ligands for the Estrogen Receptor,”Bioorganic&Medicinal Chemistry Letters, vol. 11, No. 14, 2001, pp. 1939-1942.
Katritzky. “Benzotriazole-assisted preparations of 2-(substituted amino)pyridines and pyrid-2-ones,”J. Org. Chem., vol. 62, No. 18, 1997, pp. 6210-6214.
Chemical Abstracts, vol. 115, No. 3, 1991, Abstract No. 29072d, p. 749.
Zecher; Kroehnke,Chem. Ber., vol. 94, 1961, pp. 698-704.
Chemical Abstracts, vol. 100, No. 25, 1984, Abstract No. 209593y, p. 575.
Sammour, et al.,J. Chem. U.A.R., vol. 14, 1971, pp. 581-593.
Sammour, et al.,J. Chem. U.A.R., vol. 13, 1970, pp. 421-431.

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