Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Patent
1988-11-23
1990-01-02
Shah, Mukund J.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
5142338, 514253, 514321, 514422, 514452, 514470, 544153, 544377, 544295, 544360, 546197, A61K 3134, A61K 31455, C07D49304
Patent
active
048913731
ABSTRACT:
Novel aminopropanol derivatives of 1,4:3,6-dianhydro-hexitol nitrates of the general formula I ##STR1## in which X has the meaning given in the specification, processes for their preparation and their use in preventing and treating angina pectoris, systemic hypertension and pulmonary hypertension in mammals.
REFERENCES:
patent: 4363805 (1982-12-01), Klessing
M. Leitold et al., Drug Res., 36,1454 (1986)
I. Lepran et al., L. Szekeros, "A Method of Acute Coronary Occlusion in Anesthetized Closed Chest Rats", Acta Physiologica Sci. Hungaricae 53,190 (1979).
B. G. Main and H. Tucker, Recent Advances in .beta.-Adrenergic Blocking Agents, Progress in Medicinal Chemistry 22, G. P. Ellis and G. B. West Editors, Elsevier, 1985, pp. 121 et seq.
Leitold Matyas
Stoss Peter
Yeates Rodney
Cseh C. L.
DeBenedictis Karen
Ginsberg Paul H.
Pfizer Inc.
Richardson Peter C.
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