Aminophenylcyclopropyl carboxylic acids and derivatives as...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

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Details

C514S342000, C514S365000, C514S438000, C514S567000, C544S162000, C546S269700, C548S204000, C549S077000, C562S469000

Reexamination Certificate

active

07834013

ABSTRACT:
The present invention relates generally to novel therapeutic compounds and more particularly to novel compounds, their use as GPR40 agonists, processes for their manufacture, and intermediates useful in their preparation.

REFERENCES:
patent: 5773644 (1998-06-01), Chen et al.
patent: WO02/057783 (2002-07-01), None
Vippagunta et al., Crystalline solids, 2001, Advanced Drug Delivery Reviews, 48, pp. 3-26.
Wolff et al., Burger's Medicinal Chemistry and Drug Discovery, 1994, Wiley-Interscience, Fifth Edition, vol. I: Principles and Practice, pp. 975-977.
Itoh et al., “Free fatty acids regulate insuling secretion from pancreatic beta cells through GPR40,” Nature, V422, N6928, pp. 173-176.

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