Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Patent
1992-06-10
1994-11-01
Rizzo, Nicholas S.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
540350, C07D48704, A61F 3140
Patent
active
053607988
ABSTRACT:
An antibacterial aminooxypyrrolidinylthiocarbapenem I, its production from the corresponding carbapenem V and thiol VI, its pharmaceutical formulation, and its use or combating bacteria are presented. ##STR1## (wherein R is optionally substituted amino; R.sup.1 is hydrogen or 1C to 5C alkyl; R.sup.2 is hydrogen or a conventional hydroxy protective group; R.sup.3 is hydrogen or an imino protective group or imino substituent; R.sup.4 is 1C to 5C alkylene; and R.sup.5 is hydrogen or a conventional carboxy protective group; X is a leaving group; R.sup.6 is hydrogen or a thiol protective group; and wavy lines each shows a bond in R or S configuration).
REFERENCES:
patent: 4983596 (1991-01-01), Murata et al.
patent: 5093328 (1992-03-01), Sunagawa et al.
Chemical Abstracts vol. 18 (23) 233767(a) 1994.
Makoto Kii
Sendo Yuji
Rizzo Nicholas S.
Shionogi Seiyaku Kabushiki Kaisha
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