Aminonaphthacene derivatives

Details Aminonaphthacene derivatives Aminonaphthacene derivatives

1985-04-10

1987-06-16

Brown, Johnnie R.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

536 64, A61K 3171, C07H 1524

Patent

active

046736689

ABSTRACT:
9-Aminonaphthacene derivative having the formula: ##STR1## wherein R.sup.1 and R.sup.2 are both hydrogen atoms or either one of them is a hydrogen atom and the other is hydroxy group or methoxy group; R.sup.3 is acetyl group or 1-hydroxyethyl group; R.sup.4 is a hydrogen atom; R.sup.5 is a hydrogen atom, hydroxy group, lower alkanoyloxy group, amino group, halogen-substituted lower alkanoylamino group or morpholino group; R.sup.6 is a hydrogen atom, hydroxy group, lower alkanoyloxy group or tetrahydropyranyloxy group; R.sup.7 is a hydrogen atom or methyl group; R is a hydrogen atom; and n is zero or one, which is useful as anti-cancer chemical agents with lower toxicity and with little local irritation and is able to orally be applied.

REFERENCES:
patent: 4075328 (1978-02-01), Ducep et al.
patent: 4218440 (1980-08-01), Penco et al.
patent: 4540695 (1985-09-01), Ishizumi et al.
Iwamoto, Tetrahedron Letters, No. 36, pp. 3891-3894, 1968.
Johnson et al. Cancer Trestment Reviews, 2 pp. 1-31, 1975.
Horton, Carbohydrate Research, vol. 76 (1979), pp. 269-276.

Affiliated with

Also associated with

Rating

Aminonaphthacene derivatives does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Aminonaphthacene derivatives, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Aminonaphthacene derivatives will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-683893