Aminomethylpyrrolidine derivatives having aromatic substituents

Details Aminomethylpyrrolidine derivatives having aromatic substituents Aminomethylpyrrolidine derivatives having aromatic substituents

2007-03-06

2007-03-06

Habte, Kahsay (Department: 1624)

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C548S206000, C548S215000, C548S240000, C548S314700, C548S364100, C548S524000, C548S566000, C544S179000, C544S180000, C544S181000, C544S238000, C544S333000, C544S336000, C546S279100, C546S276400

Reexamination Certificate

active

10834079

ABSTRACT:
This invention provides a quinolone derivative having potent antibacterial activity against various bacteria including drug-resistant strains which is a compound of the following formula wherein R1is an optionally substituted aromatic group, a salt of the same or a hydrate of both.In the formula, R2, R3: hydrogen atom, an alkyl group; R4, R5, R6: hydrogen atom, hydroxyl group, a halogen atom, carbamoyl group, an alkyl group, an alkoxyl group, an alkylthio group; R7, R8: hydrogen atom, an alkyl group; R9: an alkyl group, an alkenyl group, a halogenoalkyl group, a cyclic alkyl group, an aryl group, a heteroaryl group, an alkoxyl group having from 1 to 6 carbon atoms, an alkylamino group; R10:hydrogen atom, an alkylthio group; R11: hydrogen atom, amino group, hydroxyl group, thiol group, a halogenomethyl group, an alkyl group, an alkenyl group, an alkynyl group, an alkoxyl group; X1: halogen atom, a hydrogen atom; A1: nitrogen atom, C—X2; X2: hydrogen atom, amino group, a halogen atom, cyano group, an halogenomethyl group, a halogenomethoxyl group, an alkyl group, an alkenyl group, an alkynyl group, an alkoxyl group; A2, A3:>C═C (—A1═)—N(—R9)—, >N—C (—A1>)═C(—R9)—; R10and R9or R9and X2may be integrated to form a ring structure; and Y: hydrogen atom, ester forming group.

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