Aminomethylene derivaties as immunosuppressants

Details Aminomethylene derivaties as immunosuppressants Aminomethylene derivaties as immunosuppressants

1995-12-12

1997-11-11

Chang, Ceila

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514315, 514319, 514325, 514423, 546195, 546203, 546205, 546225, 546227, 546245, 548530, 548531, 548532, A61K 31445, C07D21132, C07D20710

Patent

active

056864698

ABSTRACT:
Compounds which suppress human T-lymphocyte proliferation are disclosed. The active compounds essentially contain at least the following structure: ##STR1##

REFERENCES:
Dutta et al "Proline Derivatives" CA 102: 185502f (1985) RN 2899-09-4.
Rubin et al "Synthesis of isosteric methylene-oxy Pseudopitides" Tetrahedron 42 6039-6045 (1986).
Sakurai et al "Studies of HIV protease inhibitor I" Chem. Pharm. Bull 41 1369-1377 (1993).

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