Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1991-10-31
1992-08-18
Lee, Mary C.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514435, 548526, 549 23, 549 26, A61K 3140, A61K 31385, C07D40906, C07D33504
Patent
active
051400391
ABSTRACT:
The present invention includes compounds represented by the formula: ##STR1## wherein X is O or S; R.sub.1 and R.sub.2 are independently selected from the group consisting of hydrogen, hydroxy, halo, loweralkoxy, thioalkoxy and loweralkyl; or R.sub.1 and R.sub.2 taken together can form a methylenedioxy or ethylenedioxy bridge;
REFERENCES:
patent: 3960891 (1976-06-01), Malen et al.
patent: 4066648 (1988-01-01), Oka et al.
patent: 4647579 (1987-03-01), Kabbe et al.
CA 112:98386j Preparation of 4-. . . antagonists, DeBernardis et al. p. 737, 1990.
Arendsen David L.
DeBernardis John F.
Zelle Robert E.
Abbott Laboratories
Janssen Jerry F.
Lee Mary C.
McKane Joseph K.
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