Aminomethyl peptides

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

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546146, 546275, C07D41302, C07D26100, C07D23104

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active

051226103

ABSTRACT:
Renin-inhibiting aminomethyl peptides of the formula ##STR1## in which A is H, an alkyl radical, a sulphony radical or an amino-protecting group,

REFERENCES:
patent: 4812442 (1989-03-01), Boger et al.
patent: 4818748 (1989-04-01), Bender et al.
J. Cardiovascular Pharm. Haber et al. Renin Inhibitors: A Search for Principles of Design, pp. 554-558, 1987.
J. Med. Chem. Plattner et al. Renin Inhibitors. Dipeptide Analogues . . . Proteolytic Stability, pp. 2277-2288, 1988 vol. 31.
Progress in Drug Research, Denkewalter et al. pp. 510-512, vol. 10, 1966.
J. Med. Chem. Bolis et al. Renin Inhibitors. Dipeptide Analogues . . . Seissite Bond, vol. 30, 1987, pp. 1729-1737.
Burger. Medicinal Chem. pp. 565.571, 578-581, 600-601. 1960.
Lehringer. Biochemistry. pp. 197-201, 1970.
Kempf et al. Renin Inhibitors based on . . . Journal of Med. Chem. Nov., 1987. pp. 1978-1983.

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