Aminomethyl derivatives and preparation process thereof as well

Details Aminomethyl derivatives and preparation process thereof as well Aminomethyl derivatives and preparation process thereof as well

1985-06-25

1988-03-01

Rotman, Alan L.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

546322, 564342, 564344, 564345, C07D21380, A61K 31455

Patent

active

047286598

ABSTRACT:
Disclosed herein are aminomethyl derivatives each of which is of the following general formula (I): ##STR1## wherein A represents a group --C.tbd.C-- or --CH.dbd.CH--, Y represents a group ##STR2## (in which R.sub.3 being a lower alkyl or alkoxy group or a halogen atom) or ##STR3## (in which R.sub.4 being a hydrogen atom or R.sub.3), and R.sub.1 and R.sub.2 represent individually a lower alkyl group, with a proviso that Y is other than the group ##STR4## when A means the group --CH.dbd.CH--, their preparation process and platelet aggregation inhibitors containing same.

REFERENCES:
patent: 2539801 (1951-01-01), Van Hook et al.
Chemical Abstracts, vol. 68, No. 16, Apr. 15, 1968, p. 7482, No. 77634w, Columbus, Ohio, US; N. M. Libman et al.: "Amino Alcohols of the Acetrylenic Series. VI." & Zh. Org. Khim. 4(1), 20-5 (1968).
Chemical Abstracts, vol. 84, No. 7, Feb. 16, 1976, p. 445, No. 43543f, Columbus, Ohio, US; L. I. Vereshchagin et al.: "Addition of Alcohols and Amines to Acetylenic Amino- and Brokomoketones" & Zh. Org. Khim. 1975, 11(11), 2311-15.

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