Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1982-07-26
1985-12-31
Daus, Donald G.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
548503, 548507, 514616, 544111, 544117, 514617, 544133, 544137, 514619, 544139, 544143, 514620, 544235, 544236, 514621, 544237, 544255, 514622, 544277, 544280, 548524, 544283, 544350, 548523, 544353, 546113, 548525, 546114, 546115, 548527, 546143, 546146, 548161, 546159, 546160, 548163, 546162, 546168, 548179, 546169, 546174, 548180, 546176, 546187, 548190, 546190, 548193, 548195, 548200, 548203, 548204, 548217, 548222, 548233, 548234, 548235, 548236, 548305, 548336, 548483, 548492, 548493, 548496, 564142,
Patent
active
045622019
ABSTRACT:
The present invention relates to new compounds of the formula ##STR1## where X is ##STR2## alkylene, or --S-- where R.sub.1 is hydrogen, alkyl, or aryl; W is hydrogen, hydroxy, amino, alkyloxy, aryloxy, O-alkyl, or O-aralkyl; (Y).sub.A is --CH.sub.2 NR.sub.2 R.sub.3 where R.sub.2 and R.sub.3 may be hydrogen, substituted alkyls, aryls, or together with N form a 5 to 7 membered heterocyclic group; and Ar is a substituted or unsubstituted aryl. These compounds are useful in the treatment of various cardiac arrhythmias.
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patent: 4305940 (1981-12-01), Quadro
patent: 4323691 (1982-04-01), Ours et al.
patent: 4362738 (1982-12-01), Keck et al.
Li et al., Chemical Abstracts, vol. 92, p. 61, Abstract 121950t (1980).
Boucherle, Chimie Therapeutique (1967) No. 6, pp. 410-414.
Sun, C. et al., Yao Hsueh Hsueh Pao., vol. 16(8), 1981 pp. 564-570.
Matier William L.
Stout David M.
American Hospital Supply Corporation
Barbeau Donald L.
Daus Donald G.
Fato Gildo E.
Teoli, Jr. William A.
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