Aminomethyl benzanilides

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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548503, 548507, 514616, 544111, 544117, 514617, 544133, 544137, 514619, 544139, 544143, 514620, 544235, 544236, 514621, 544237, 544255, 514622, 544277, 544280, 548524, 544283, 544350, 548523, 544353, 546113, 548525, 546114, 546115, 548527, 546143, 546146, 548161, 546159, 546160, 548163, 546162, 546168, 548179, 546169, 546174, 548180, 546176, 546187, 548190, 546190, 548193, 548195, 548200, 548203, 548204, 548217, 548222, 548233, 548234, 548235, 548236, 548305, 548336, 548483, 548492, 548493, 548496, 564142,

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045622019

ABSTRACT:
The present invention relates to new compounds of the formula ##STR1## where X is ##STR2## alkylene, or --S-- where R.sub.1 is hydrogen, alkyl, or aryl; W is hydrogen, hydroxy, amino, alkyloxy, aryloxy, O-alkyl, or O-aralkyl; (Y).sub.A is --CH.sub.2 NR.sub.2 R.sub.3 where R.sub.2 and R.sub.3 may be hydrogen, substituted alkyls, aryls, or together with N form a 5 to 7 membered heterocyclic group; and Ar is a substituted or unsubstituted aryl. These compounds are useful in the treatment of various cardiac arrhythmias.

REFERENCES:
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patent: 3287363 (1966-11-01), Palopoli et al.
patent: 4305940 (1981-12-01), Quadro
patent: 4323691 (1982-04-01), Ours et al.
patent: 4362738 (1982-12-01), Keck et al.
Li et al., Chemical Abstracts, vol. 92, p. 61, Abstract 121950t (1980).
Boucherle, Chimie Therapeutique (1967) No. 6, pp. 410-414.
Sun, C. et al., Yao Hsueh Hsueh Pao., vol. 16(8), 1981 pp. 564-570.

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