Aminoketone asymmetric reductase and nucleic acid thereof

Chemistry: molecular biology and microbiology – Enzyme – proenzyme; compositions thereof; process for... – Oxidoreductase

Reexamination Certificate

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C435S128000, C435S169000, C435S170000

Reexamination Certificate

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10469682

ABSTRACT:
A protein, which is an aminoketone asymmetric reductase, having an effect of producing d-pseudoephedrine by acting on 1-2-methylaminopropiophenone, and having the following physiochemical properties:substrate: 1-2-methylaminopropiophenoneoptimum pH: pH 8.1optimum temperature: 55° C.coenzyme: NADPmolecular weight: about 28500 Da homotetramer and a nucleic acid coding the protein.

REFERENCES:
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patent: WO 01/73100 (2001-10-01), None
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English Translation of the International Preliminary Examination Report issued for PCT application No. PCT/JP02/01928 filed on Mar. 1, 2002. (4 pages).

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