Aminoglycosides as antibiotics

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai

Reexamination Certificate

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C514S025000, C514S035000, C536S016800, C536S017200, C536S017500, C536S017600, C536S017900

Reexamination Certificate

active

10415732

ABSTRACT:
The present invention provides aminoglycosides and pharmaceutical compositions that include the aminoglycosides. The aminogylcosides are useful to treat or prevent infectious diseases (e.g., bacterial infections) in a mammal (e.g., human).

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Goodman & Gilman's: The Pharmacological Basis of Therapeutics, 10th Edition, McGraw-Hill Medical Publishing Division, 2001, pp. 54-56.
Gov et al., Peptides, 2001, 22:1609-1620.
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Ghiselli et al., Eur. J. Vasc. Endovasc. Surg., 2004, 27:603-607.
Haddad, J. , et al., “Design of Novel Antibiotics that Bind to the Ribosomal Acyltransfer Site”,J. Am. Chem. Soc., 124, (2002),3229-3237.
Kuwahara, R. , et al., “Synthesis of Dibekacin Analogs Containing 3-oxa-and 3-aza-2,3,4-trideoxy-D-glycero-hexopyranose”,Carbohydrate Research, 293, (1996), 15-30.

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