Aminoglycoside steroids, a process for their preparation, their

Details Aminoglycoside steroids, a process for their preparation, their Aminoglycoside steroids, a process for their preparation, their

1987-10-29

1990-04-24

Griffin, Ronald W.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

536 5, 536 174, 536 187, 514 27, A61K 31705

Patent

active

049200992

ABSTRACT:
##STR1## Compounds I [R.sub.1 =H or C.sub.1 -C.sub.3 alkyl, R.sub.2 =an (alkyl-substituted) aminodeoxy or aminodideoxy or aminotrideoxy sugar residue of the D and L series, the glycosidic linkage being .alpha. or .beta.] and their pharmaceutically acceptable salts are useful as antihypertensive agents. Their preparation and use as well as pharmaceutical compositions containing them are also described.

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patent: 3914213 (1975-10-01), Stache et al.
patent: 4088757 (1978-05-01), Petersen
Lucas et al; J.A.C.S. 82: 5688-5693 (1960).
Katzung et al; Experientia 26(11): 1189-91 (1970).
Davisson et al; Chemical Abstracts 78: 119146c (1973).
Rohrer et al; J.A.C.S. 98(20): 6308-6312 (1976).
Makarevich et al; Chemical Abstracts 102: 185349m (1985).

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