Aminoglycoside-polyamine displacers and methods of use in...

Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives

Reexamination Certificate

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C536S013600, C536S013700, C536S013800, C536S017900, C536S127000

Reexamination Certificate

active

07439343

ABSTRACT:
Aminoglycoside-polyamines are disclosed along with methods of use thereof in displacement chromatography and as DNA-binding ligands. The aminoglycoside-polyamines are derivatives of carbohydrates, such as sugars, amino sugars, deoxysugars, glycosides, nucleosides and their substituted counterparts. The subject polyamines possess agroup in place of at least one hydrogen atom of at least one hydroxyl group of the carbohydrate compound. In these compounds R1is an alkyl group or an azaalkyl group, and R2is a primary or secondary amino group.

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