Aminoglycoside antibiotics and methods of using same

Details Aminoglycoside antibiotics and methods of using same Aminoglycoside antibiotics and methods of using same

2007-07-17

2007-07-17

Jiang, Shaojia Anna (Department: 1623)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

C514S036000, C514S039000, C514S041000, C514S025000, C536S016800, C536S017200, C536S017500, C536S017900, C536S013200, C536S023100, C536S016600, C536S024100, C435S006120, C435S069100, C435S194000, C435S069300

Reexamination Certificate

active

10941623

ABSTRACT:
The present invention relates to aminoglycoside compounds having antibiotic activity. Moreover, the present invention relates to L-aminoglycoside compounds and diastereomers thereof which posses antibiotic activity and are not susceptible to development of resistant bacterial strains. The present invention also relates to methods of treatment and pharmaceutical compositions that utilize or comprise one or more of aminoglycoside compounds provided by the invention.

REFERENCES:
patent: 4008362 (1977-02-01), Akita et al.
patent: 4065616 (1977-12-01), Umezawa et al.
patent: 4252970 (1981-02-01), Magerlein
patent: 4281107 (1981-07-01), Suami
patent: 6482802 (2002-11-01), Hu et al.
Wang et al. “Specificity of aminoglycoside binding to RNA constructs derives from the 16S rRNA decoding region and the HIV-RRE activator region.” Biochemistry, 36, 768-779, 1997.

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