Aminoglycoside 66-40C, method for its manufacture, method for it

Details Aminoglycoside 66-40C, method for its manufacture, method for it Aminoglycoside 66-40C, method for its manufacture, method for it

1975-05-02

1977-02-22

Brown, Johnnie R.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

424180, 536 10, 195 31R, C07H 1522

Patent

active

040093280

ABSTRACT:
Aminoglycoside 66-40C, a minor product produced by the fermentation of Micromonospora inyoensis, is separated from said fermentation mixture, and is used as an intermediate in preparing the known antibiotic, sisomicin, as well as 6' -N-alkylsisomicins having antibacterial activity. Claimed are Aminoglycoside 66-40C as well as 6' -N-t-alkylsisomicins having a tertiary carbon bonded to the 6' -nitrogen.

REFERENCES:
patent: 3651042 (1972-03-01), Marquez et al.
patent: 3832286 (1974-08-01), Weinstein et al.
patent: 3880828 (1975-04-01), Mallams et al.
patent: 3929762 (1975-12-01), Umezawa et al.

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