Aminoeverninomicin and derivatives thereof

Details Aminoeverninomicin and derivatives thereof Aminoeverninomicin and derivatives thereof

1977-09-16

1978-12-12

Brown, Johnnie R.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

424180, C07H 1704

Patent

active

041297202

ABSTRACT:
Everninomicin B, C or D may be converted to amino derivatives by reductive means. The amino derivatives may, subsequently, be converted to novel N-acyl, N-alkyl or N,N-dialkyl derivatives. Alternatively, everninomicins B, C or D may be converted to N-acyl-N-hydroxylamino derivatives also by reductive means. The derivatives so-produced and the non-toxic pharmaceutically acceptable cationic salts thereof are novel and are antibacterial agents.

REFERENCES:
patent: 3920629 (1975-11-01), Ganguly et al.
patent: 3998708 (1976-12-01), Kabasakalian et al.
patent: 4006225 (1977-02-01), Ganguly et al.

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