Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Patent
1985-12-24
1987-05-26
Daus, Donald G.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
544360, 544357, 544295, 544124, 546334, 546281, C07D40106, C07D40306, A61K 31495
Patent
active
046686797
ABSTRACT:
The invention relates to compounds of the formula: ##STR1## and pharmaceutically acceptable salts thereof, in which X represents either --CH.dbd. or --N.dbd., R.sub.1 represents an alkyl radical having 1 to 5 carbon atoms, R.sub.2 represents hydrogen and R.sub.3 is an alkyl radical having 1 to 5 carbon atoms, or R.sub.2 and R.sub.3, together with the nitrogen atom to which they are bonded, represent a heterocyclic radical, such as pyrrolidinyl, morpholino, 4-phenyl-piperazinyl, in which the phenyl radical can carry one or more substituents, such as a halogen atom, an alkyl or alkoxy radical having 1 to 5 carbon atoms or the trifluoromethyl radical, or represents 4-(2-pyrimidinyl)-piperazinyl, having anti-bronchoconstrictory properties.
REFERENCES:
patent: 4358455 (1982-11-01), Atkinson et al.
patent: 4460580 (1984-07-01), Ostermayer et al.
patent: 4578467 (1986-03-01), Bonacchi et al.
Derwent Abstract 12797w/08 of BE 820,242 16-Jan.-75.
Carlier Patrick
Monteil Andr/e/ J.
Simond Jacques A. L.
Daus Donald G.
Riom Laboratories C.E.R.M.
Teoli, Jr. William A.
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