Aminoethanol derivatives

Details Aminoethanol derivatives Aminoethanol derivatives

2006-01-03

2006-01-03

Kumar, Shailendra (Department: 1621)

Organic compounds -- part of the class 532-570 series

Organic compounds

Amino nitrogen containing

C560S157000, C546S157000, C548S492000, C549S057000, C514S617000, C514S478000, C514S443000, C514S412000, C514S311000

Reexamination Certificate

active

06982348

ABSTRACT:
The present invention provides a pharmaceutical agent having cholesteryl ester transfer protein inhibitory action and useful as a blood lipid lowering agent and the like. The present invention relates to a compound represented by the formulawherein Ar1is an aromatic ring group optionally having substituents, Ar2is an aromatic ring group having substituents, OR″ is an optionally protected hydroxyl group, R is an acyl group, R′ is a hydrogen atom or a hydrocarbon group optionally having substituents, or a salt thereof, and a pharmaceutical composition containing a compound of the formula (I) or a salt thereof or a prodrug thereof.

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Piron, et al. “New Methods for Solid Phase Peptide Synthesis of Transition-State Analog Inhibitors of HIV-1 Protease and DPP-IV” Letters in Peptide Science 2: 229-232 (1995).

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