Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Patent
1987-01-15
1989-09-12
Lovering, Richard D.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
424450, 4284022, 514 2, 514 78, 514305, 514535, 514547, 514556, 514821, 530330, A61K 31225, A61K 3702, A61K 3764, C08G 6908
Patent
active
048660400
ABSTRACT:
Carnitine, aminocarnitine and cysteic acid serve as carriers to bring pharmaceutically active compounds to desired sites in the body, e.g. skeletal muscle or the heart. The pharmaceutically active compound can be a protease inhibitor, a cardioactive drug for combating arrythmia, etc. The linkage is chemical through one or more alcohol, carboxyl or amine groups using reagents such as glutaraldehyde, dicarboxylic acid anhydrides and acid halides and carbodiimides. Carnitine derivatives are also incorporated into liposomes which are then used as carriers of active pharmaceutical agents.
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Kesner Leo
Stracher Alfred
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