Organic compounds -- part of the class 532-570 series – Organic compounds – Unsubstituted hydrocarbyl chain between the ring and the -c-...
Reexamination Certificate
2005-04-05
2005-04-05
Tucker, Philip C. (Department: 1712)
Organic compounds -- part of the class 532-570 series
Organic compounds
Unsubstituted hydrocarbyl chain between the ring and the -c-...
C534S016000
Reexamination Certificate
active
06875864
ABSTRACT:
Novel metal-chelate complexes comprising aminocarboxylate ligands including substituted aromatic amide moieties, such as those having the formulawherein R13, A1, R1and R2are as defined herein, are disclosed.
REFERENCES:
patent: 4631337 (1986-12-01), Tomalia et al.
patent: 4647447 (1987-03-01), Gries et al.
patent: 4687659 (1987-08-01), Quay
patent: 4859451 (1989-08-01), Quay et al.
patent: 4885363 (1989-12-01), Tweedle et al.
patent: 4889755 (1989-12-01), Charbonneau
patent: 4957939 (1990-09-01), Gries et al.
patent: 4963344 (1990-10-01), Gries et al.
patent: 4983376 (1991-01-01), Sherry
patent: 5021236 (1991-06-01), Gries et al.
patent: 5573752 (1996-11-01), Ranganathan et al.
patent: 5639879 (1997-06-01), Mease et al.
patent: 20020127629 (2002-09-01), Bugdanov et al.
patent: 7899587 (1988-03-01), None
patent: 3148589 (1989-09-01), None
patent: 6107390 (1991-02-01), None
patent: 2039846 (1991-10-01), None
patent: 0230893 (1987-08-01), None
patent: 0325762 (1989-08-01), None
patent: 450742 (1991-10-01), None
patent: 227421 (1990-10-01), None
patent: WO8905802 (1989-06-01), None
patent: WO92/04336 (1992-03-01), None
Wedeking et al., Society of Magnetic Resonance in Medicine, Book of Abstracts, 8th Annual Meeting, pp. 801-802, Aug. 12-18, 1989.*
Villringer et al., “Dynamic Imaging with Lanthanide Chelates in Normal Brain: Contrast Due to Magnetic Susceptibility Effects”, Magnetic Resonance in Medicine. 6. 164-174 (1988).
Shehadi, “Contrast Media Adverse Reactions: Occurrence, Recurrence, and Distribution Patterns”, Diagnostic Radiology, vol. 143, No. 1, pp. 11-17 (Ann 1982).
Bettmann, “Angiographic Contrast Agents: Conventional and New Media Compared”. AJE. 139, pp. 787-794 (Oct. 1982).
Bettmann et al., “Recent Advances in Contrast Agents”, Radiologic Clinics of North America. vol. 24, No. 3, pp. 347-357 (Sep. 1986).
Wedeking et al., “Comparison of the Biodistribution of153Gd-Labeled Gd(DTPA)2-, Gd(DOTA)” and Gd(Acetate)n in Mice, Mud. Med. Biol., vol. 15, No. 4. nn. 395-402 (1988).
Tweedle et al., “Reaction of Gadolinium Chelates with Endogenously Available Tons”. Magnetic Resonance Imaging. vol. 9. pp. 409-415 (1991).
Tweedle, “Work in Progress Toward Nonionic Macrocyclic Gadolinium(III) Complexes”, in Contrast and Contrast Agents in Magnetic Resonance Imaging, edited by P. A. Rink, European Workshop on Magnetic Resonance in Medicine. pp. 65-73 (1989).
Brechbiel et al., “Synthesis of 1.(p-Isothiocyanatobenzyl) Derivatives of DTPA and EDTA. Antibody Labeling and Tumor-Imaging Studies”, Inorg. Chem., 25, pp. 2772-2781 (1986).
Hoey et al., “Chemistry of X-ray Contrast Media”, Handbook of Experimental Pharmpcology. n. 23-125 (1984).
Wedeking et al., “Biodistribution and Excretion of New Gd-Complexes in Mice”, p. 801 and Multi-Tissue Pharmacokentic Evaluation of MRI Contrast Agents; p. 802, Society of Magnetic Resonance in Medicine, 8th Annual Meeting, The RAI Consrescentrum. Amsterdam. The Netherlands (Aug. 12-18. 1989).
Cavagna et al., “Biliary Agents: New Formulations”, International Symposium & Course, Liver Imaging—Present and Future in MRI, CT & US, Harvard Medical School—Boston. Massachusetts, 3 pages (Jun. 25-27. 19901.
Broan et al., “Structure and solution stability of indium and gallium complexes of 1,4,7-triazacyclononanetriacetate and yttrium complexes of 1,4,7,10-tetra-azacyclododecanetetracetate and related ligands . . . ”, J. Chem. Soc., Perkin Trans. 2.No. 1. pp. 87-99(1991).
Dischino et al., “Synthesis of Nonionic Gadolinium Chelates Useful as Contrast Agents for Magnetic Resonance Imaging”, Inorganic Chemistry, vol. 30, No. 6, p. 1265-1269 (1991).
Society of Magnetic Resonance in Medicine, Book of Abstracts, 8th Annual Meeting, Aug. 12-18, 1989.
Kang Sang I.
Marinelli Edmund R.
Pillai Radhakrishna K.
Ranganathan Ramachandran S.
Tweedle Michael F.
Bracco International B.V.
Kramer Levin Naftalis & Frankel LLP
Tucker Philip C.
LandOfFree
Aminocarboxylate ligands having substituted aromatic amide... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Aminocarboxylate ligands having substituted aromatic amide..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Aminocarboxylate ligands having substituted aromatic amide... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3386135