Aminobenzoic acid derivatives

Details Aminobenzoic acid derivatives Aminobenzoic acid derivatives

1995-06-07

1997-02-04

Rotman, Alan L.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carboxylic acids and salts thereof

560 46, 546124, C07C22934

Patent

active

055999727

ABSTRACT:
An aminobenzoic acid derivative represented by the following general formulas (I), (I-2) or (I-3), or a pharmacologically acceptable salt thereof, which exhibits a serotonin antagonism and an acetylcholine release accelerating activity at a well-balanced activity ratio and which is efficacious as a drug for patients with gastrointestinal unindentified complaints: ##STR1## wherein R.sup.1 represents a group such as an alkynyl or cyanoalkyl group; R.sup.2 represents a group such as an amino or acylamino group; R.sup.3 represents a halogen atom; X represents --O-- or --NH--; and A represents an oxygen or sulfur atom.

REFERENCES:
Miyazawa et al., Chemical Abstracts, vol. 123(13), abst. No. 169, 517-t, Sep., 25, 1995.
Miyazawa et al., Chemical Abstracts, vol. 120(9), abst. No. 106, 775-t, Feb. 28, 1994.

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