Aminobenzlpropranolol and pharmaceutical preparation thereof

Details Aminobenzlpropranolol and pharmaceutical preparation thereof Aminobenzlpropranolol and pharmaceutical preparation thereof

1980-11-05

1983-03-08

Helfin, Bernard

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Recombinant or stably-transformed bacterium encoding one or...

424316, 26050117, 564350, 564349, 564381, C07C 8728, A61K 31135

Patent

active

043761259

ABSTRACT:
1-(p-Amino-.alpha.,.alpha.-dimethylphenethylamino)-3-(1-naphthoxy)-2-propan ol, 1-(p-hydroxy-.alpha.,.alpha.-dimethylphenethylamino)-3-(1-naphthoxy)-2-pro panol, 1-(p-methyl-.alpha.,.alpha.-dimethylphenethylamino)-3-(1-naphthoxy)-2-prop anol, 1-(p-methoxy-.alpha.,.alpha.-dimethylphenethylamino)-3-(1-naphthoxy)-2-pro panol and the pharmaceutically acceptable acid addition salts thereof are effective, long lasting .beta.-adrenergic blocking agents and areas of indication are hypertension, angina pectoris, cardiac arrythmia, and the like.

REFERENCES:
patent: 2590079 (1952-03-01), Abell et al.
patent: 3337628 (1967-08-01), Crowther et al.
patent: 4161542 (1979-07-01), Carlsson et al.
Terasaki et al., Proc. Natl. Acad. Sci. USA, vol. 76, No. 12, pp. 6401-6405, Dec. 1979.
Crowther et al., Jour. Med. Chem., vol. 11 (1968), pp. 1009-1013.

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