Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Reexamination Certificate
2006-04-18
2006-04-18
Powers, Fiona T. (Department: 1626)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
C514S254060, C514S322000, C544S121000, C544S370000, C546S199000
Reexamination Certificate
active
07030113
ABSTRACT:
The present invention discloses compounds of formula Iwherein Ar, Z, m, n, p, R1and R8are herein defined, said compounds being novel antagonists for melanin-concentrating hormone (MCH), as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising such MCH antagonists as well as methods of using them to treat obesity, metabolic disorders, eating disorders such as hyperphagia, and diabetes.
REFERENCES:
patent: 5908830 (1999-06-01), Smith et al.
patent: 2003/0212070 (2003-11-01), Schwink et al.
patent: 2003/0216390 (2003-11-01), DeSimone et al.
patent: 2004/0192693 (2004-09-01), Shwink et al.
patent: 2004/0198731 (2004-10-01), Schwink et al.
patent: 2004/0198732 (2004-10-01), Schwink et al.
patent: 2004/0198733 (2004-10-01), Schwink et al.
patent: 03/015769 (2003-02-01), None
patent: 03/59289 (2003-07-01), None
patent: 2004/011440 (2004-02-01), None
patent: 2004/031177 (2004-04-01), None
patent: WO-2004100875 (2004-11-01), None
Masako Shimada et al, Mice Lacking Melanin-Concentraling Hormone are Hypophagic and Lean,Nature1998, 396: 670-674.
Beth Borowsky et al., Antidepressant, Anxiolytic and Anorectic Effects of a Melanin-Concentrating Hormone-1 Receptor Antagonists,Nature Medicine2002, 8:825-828.
PCT International Search Report dated Sep. 30, 2004 for corresponding PCT Application No. PCT/US2004/032494 - 4 Pages.
Burnett Duane A.
Sasikumar Thavalakulamgara K.
Lee William Y.
Powers Fiona T.
Schering Corporation
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