Aminobenzene compounds to prevent nerve cell degradation

Details Aminobenzene compounds to prevent nerve cell degradation Aminobenzene compounds to prevent nerve cell degradation

1994-06-28

1996-12-03

Criares, Theodore J.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514320, 514318, 514326, 514329, 514336, 514430, 514449, 514450, 5142312, 514304, 514357, A61K 31445, A61K 3144, A61K 3138, A61K331535

Patent

active

055808832

ABSTRACT:
A compound useful for central antioxidant having inhibitory activity of degeneration and necrocytosis of cerebral cells of the formula (I): ##STR1## wherein A and B are independently (1) a group of the formula: ##STR2## wherein R.sub.1 and R.sub.2 are independently hydrogen atom, an optionally substituted hydrocarbon residue or an optionally substituted heterocyclic group, or R.sub.1 together with R.sub.2 and the nitrogen atom to which they are bound may form a cyclic amino group, provided that both R.sub.1 and R.sub.2 are not hydrogen atom at the same time, or (2) a group of the formula: ##STR3## wherein D is O or S, R.sub.3 is hydrogen atom, an optionally substituted hydrocarbon residue or an optionally substituted acyl group, m is 1, 2, or 3 and n is 0, 1, 2, 3 or 4;

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Chemical Abstracts, vol. 63, 1965, 46-Dyes.
P. Caubere, "Arynic and SnAr Reactions of Polyhalogenobenzenes"-VI12, Tetrahydron., vol. 33, pp. 955-959, Dec. 13, 1976.
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