Aminoanthraquinone derivatives to combat multidrug resistance

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

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5142375, 5142395, 514252, 514255, 514316, 514319, 514325, 514649, 544 79, 544156, 544357, 544380, 546191, 546204, 552247, 552255, A61K 31135, A61K 3155, A61K 31535, A61K 31445

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054362431

ABSTRACT:
Potentiating agents inhibit the development of multidrug resistance, reduce drug-resistance in drug-resistant tumors, or sensitize tumors to antineoplastic drugs, thereby potentiating the effect of antineoplastic agents. The potentiating agents are aminoanthraquinones, preferably 1,4-bis(N-substituted) amino anthraquinones, and pharmaceutically acceptable salts thereof.

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