Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Reexamination Certificate
2008-02-27
2010-11-09
Padmanabhan, Sreeni (Department: 1627)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
C514S252100, C514S256000, C514S277000, C514S365000, C514S461000, C540S467000, C540S470000, C544S002000, C544S003000, C544S224000, C544S238000, C544S336000, C546S268100, C546S268400, C548S146000, C548S206000, C548S215000, C548S240000, C548S400000, C549S013000, C549S029000, C549S200000, C549S429000
Reexamination Certificate
active
07829563
ABSTRACT:
The present invention relates to compounds of formula Iwherein Ar1, Ar2, Ar3, n, andR1to R8are as defined herein and to pharmaceutically suitable acid addition salts, optically pure enantiomers, racemates or diastereomeric mixtures thereof. These compounds are orexin receptor antagonists and may be useful in the treatment of disorders, in which orexin pathways are involved, like sleep disorders.
REFERENCES:
patent: 5290799 (1994-03-01), Misra et al.
patent: 7078565 (2006-07-01), Chan et al.
patent: 2003/0144215 (2003-07-01), Ksander et al.
patent: WO 2007/025709 (2007-03-01), None
Gobbi Luca
Knust Henner
Malherbe Parichehr
Nettekoven Matthias
Pinard Emmanuel
Hoffmann-La Roche Inc.
Johnston George W.
Padmanabhan Sreeni
Pihonak Sarah
Prior Kimberly J.
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