Aminoalkylthiodibenzothiepins and related compounds

Details Aminoalkylthiodibenzothiepins and related compounds Aminoalkylthiodibenzothiepins and related compounds

1989-12-20

1991-04-09

Waddell, Frederick E.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C07D33714

Patent

active

050066641

ABSTRACT:
Novel aminoalkylthiodibenzothiepins and related compounds, physiologically tolerable acid addition salts thereof, a method of preparing same, pharmaceutical and veterinary preparations including same and methods of treating by administering same are disclosed. These compounds are useful as antidepressant, analgetic, and anticonvulsant agents.

REFERENCES:
March, Advanced Organic Chemistry, 2nd Ed., pp. 374-375, 1977, McGraw-Hill Publ.
Ong et al., "Tricyclics . . . [[(Alkylamino)ethyl]thio]dibenzo[b,f]thiepins", J. Med. Chem., 1982, vol. 25, No. 10, p. 1151.
Seidl et al., "Reaction of Thioxanthylium . . . ", Dept. of Chemistry, Mass. Inst. of Tech., Jun. 1967.
Patai, The Chemistry of the Thiol Group, 1974, John Wiley & Sons Publ., pp. 765-767.

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