Aminoalkylphenols, methods of using and making the same

Details Aminoalkylphenols, methods of using and making the same Aminoalkylphenols, methods of using and making the same

2009-08-13

2010-11-16

O'Sullivan, Peter G (Department: 1621)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Nitrogen containing other than solely as a nitrogen in an...

C514S649000, C514S650000, C514S654000, C514S655000, C564S337000, C564S366000, C564S373000, C564S374000, C564S381000, C564S382000, C564S390000

Reexamination Certificate

active

07834062

ABSTRACT:
The present invention relates to Mannich base antimalarial aminoalkylphenol compounds and their use against protozoa of the genusPlasmodium, particularly emerging strains of drug-resistant Plasmodia. This invention further relates to compositions containing such compounds and a process for making the compounds. This and other aspects of the invention are realized upon review of the entire specification.

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Schmidt et al. “Antimalarial Activities of WR-194,965, an α-Amino-o-Cresol Derivative”, Antimicrobial Agents and Chemotherapy, 1978, Vol. 14, pp. 672-679.
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