Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1994-08-03
1997-09-09
Ford, John M
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
564256, 564640, 564211, 564213, 5642278, 5642275, 5642358, 5642378, 564336, 564357, 564431, 564450, 564183, 564422, 564423, 564392, 564396, 564315, 564322, 564326, 564212, 540483, 540467, 540450, 540544, 540609, 540480, 540482, 540603, 546210, 546229, 546221, 5483124, 5483137, 5483147, 548539, 5483361, 5483415, 544 56, 544122, 544162, 544 60, 544130, 544187, 544189, C07C25158, C07C23361, A61K 31415, A61K 3115
Patent
active
056657560
ABSTRACT:
Novel aminoalkyloximes of the formula ##STR1## wherein: a. X is hydrogen, loweralkyl, loweralkoxy, halogen, trifluoromethyl, or a group of the formula ##STR2## wherein Y is hydrogen or loweralkyl, and p is 1 or 2; b. A is a group of the formula ##STR3## c. R.sup.1 and R.sup.2 are independently hydrogen or lowerakyl; and d. m is 2 to 6 and n is 0, or 2 to 6, inclusive, serotonin reuptake inhibitors, useful for treating depression and obsessive compulsive disorders are described. Also described are precursors of and processes for the preparation of such aminoakyloximes.
REFERENCES:
patent: 3636111 (1972-01-01), Karten
patent: 4085225 (1978-04-01), Welle
patent: 4239901 (1980-12-01), Rainer
patent: 4297359 (1981-10-01), van Zorge
patent: 4328227 (1982-05-01), Ulrich
patent: 4352804 (1982-10-01), van Zorge
patent: 4851423 (1989-07-01), Girijavaliabhan
patent: 5064824 (1991-11-01), Acton
patent: 5126444 (1992-06-01), Acton
T. Sakamoto, et al., Chemical and Pharmaceutical Bulletin, 34, 2754 (1986) published in Japan and entitled "Heteroaromatic Ring Systems, VIII. Synthesis of 3-Substituted Isocoumarins from O-Halobenzoic Acid Derivatives".
A. N. Tischler and T. J. Lanza, Tetrahedron Letters, 27, 1653 (1986), published in Great Britain and entitled "6-Substituted Indoles from O-Halonitrobenzenes".
Freed Brian S.
Hamer R. Richard L.
Shutske Gregory M.
Tomer, IV John D.
Ford John M
Genoni Kenneth A.
Hoechst Marion Roussel Inc.
Simmons Edlyn S.
Wittekind Raymond R.
LandOfFree
Aminoalkyloximes useful in the treatment of depression and obses does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Aminoalkyloximes useful in the treatment of depression and obses, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Aminoalkyloximes useful in the treatment of depression and obses will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-70522