Aminoalkylindans and use as hypotensive agents

Details Aminoalkylindans and use as hypotensive agents Aminoalkylindans and use as hypotensive agents

1979-01-12

1980-11-04

Waddell, Frederick E.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Recombinant or stably-transformed bacterium encoding one or...

424330, 564170, 564177, 564182, 564185, 564374, A61K 31165, A61K 31135, C07C10320, C07C 8728

Patent

active

042320143

ABSTRACT:
Aminoalkylindans of the formula ##STR1## wherein A represents an alkylene group having 2 to 5 carbons in a straight chain, R.sub.1 represents a lower alkyl having 1 to 3 carbons or is a lower alkoxy having 1 to 3 carbons, B represents --CH.sub.2 -- or ##STR2## and R.sub.2 represents phenyl or phenyl-lower alkyl and the phenyl group in such substituents is unsubstituted or is substituted with 1 to 3 lower alkoxy groups, and acid addition salts of the amines.
The compounds have hypotensive activity.

REFERENCES:
J. Pharm. Sciences, 67, 314, Mar. 1978.
J. Org. Chem., 39, 2852, (1974).

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