Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Recombinant or stably-transformed bacterium encoding one or...
Patent
1976-10-20
1977-09-20
Hines, Robert V.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Recombinant or stably-transformed bacterium encoding one or...
260326R, 260465F, 26050118, 260559P, 260562P, 260570R, 560 60, 424330, C07C 920, C07C 924
Patent
active
040498255
ABSTRACT:
Diphenylmethoxyethylamines of the general formula ##STR1## in which R.sub.1 represents a fluorine, bromine or chlorine atom, R.sub.2 represents a hydrogen or fluorine atom and R.sub.3 represents a hydrogen, fluorine or chlorine atom, with the provisos that R.sub.3 is a hydrogen atom when R.sub.2 is a fluorine atom, R.sub.1 is a fluorine atom when R.sub.3 is a chlorine atom and R.sub.1 is a fluorine or bromine atom when R.sub.2 and R.sub.3 both are hydrogen atoms, and their non-toxic acid addition salts are disclosed. The compounds have dopaminergic properties and their use is indicated for treating the Parkinson syndrome. Compositions for such use are disclosed.
REFERENCES:
patent: 2527963 (1950-10-01), Rieverchi
patent: 3266988 (1966-08-01), Saunders
patent: 3565955 (1971-02-01), Ehrhart et al.
patent: 3666811 (1972-05-01), Stett
Adams Bruce L.
Burns Robert E.
Gist-Brocades N.V.
Hines Robert V.
Lobato Emmanuel J.
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