Aminoalkylethers

Details Aminoalkylethers Aminoalkylethers

1973-03-06

1977-01-18

Hines, Robert V.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

260326R, 260465F, 260473A, 26050118, 260559P, 260562P, 424316, 424330, C07C 9306

Patent

active

040039323

ABSTRACT:
Diphenylmethoxyethylamines of the general formula ##STR1## in which R.sub.1 represents a fluorine, bromine or chlorine atom, R.sub.2 represents a hydrogen or fluorine atom and R.sub.3 represents a hydrogen, fluorine or chlorine atom, with the provisos that R.sub.3 is a hydrogen atom when R.sub.2 is a fluorine atom, R.sub.1 is a fluorine atom when R.sub.3 is a chlorine atom and R.sub.1 is a fluorine or bromine atom when R.sub.2 and R.sub.3 both are hydrogen atoms, and their non-toxic acid addition salts are disclosed. The compounds have dopaminergic properties and their use is indicated for treating the Parkinson syndrome. Compositions for such use are disclosed.

REFERENCES:
patent: 2527963 (1950-10-01), Rieveschl
patent: 3266988 (1966-08-01), Sannders
patent: 3565955 (1971-02-01), Ehrhart et al.
patent: 3666811 (1972-05-01), Stelt
Burger, "Medicinal Chemistry", 2nd Ed. pp. 42-43 and 505-506 (1960).

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