Aminoalkyl-substituted cycloalkylamine platinum (II) complexes

Details Aminoalkyl-substituted cycloalkylamine platinum (II) complexes Aminoalkyl-substituted cycloalkylamine platinum (II) complexes

1990-07-31

1992-05-26

Rivers, Diana

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

548402, 548950, 548955, A61K 31555, C07F 1500

Patent

active

051168316

ABSTRACT:
Square-planar four-coordinate complexes of cis-platinum (II) with neutral bidentate aminoalkyl-substituted cycloalkylamine ligands and bromo-, chloro-, iodo-, nitrato-, oxalato-, or malanato-ligands possess antimicrobial activity as well as activity against transplanted L1210 and P388 murine leukemia cell lines.

REFERENCES:
patent: 4410544 (1983-10-01), Berg et al.
patent: 4584316 (1986-04-01), Rosenberg et al.
patent: 4661516 (1987-04-01), Brown et al.
patent: 4704464 (1987-11-01), Brunner et al.
patent: 4716157 (1987-12-01), Bitha et al.
patent: 4822892 (1989-04-01), Honda et al.
patent: 4939256 (1990-07-01), Takamatsu et al.
patent: 4970324 (1990-11-01), Hoeschele et al.
Inagaki et al., Inorganica Chim. Acta, 37: L547-L548 (1979).
Proc. of the Am. Assoc. of Cancer Res., Abstr. 652, p. 166, Hacker et al.
Sosnovsky et al., Chemical Abstracts, vol. 101(17):143678s Oct. 22,1984.
Connors et al., Chemical Abstracts, vol. 78: 79753q (1973).
Simon et al., Revue Roumaine Biochemie, vol. 14(2), pp. 117-125 (1977).
Tobe et al., Chemical Abstracts, vol. 80: 55897e (1974).
Douple et al., Chemical Abstracts, vol. 89: 157244t (1978).
Honda et al., Chemical Abstracts, vol. 105: 97698f (1986).
Honda et al., Chemical Abstracts, vol. 108: 106740s, 106741t (1988).
Tanabe Seiyaku KK, Derwent Abstract 85-272741/44 of Japan 184,015, Sep. 19, 1985.
Chugai Pharmaceutical KK, Derwent Abstract 85-240374/39 of Japan 158,195, Aug. 19, 1985.
Tanabe Seiyaku KK (II), Derwent Abstract 84-131256/21 of Japan 67,262, Apr. 16, 1984.
Simon et al., Chemical Abstracts, vol. 87, 145547q (1977).
Bystrenina et al., Chemical Abstracts, vol. 96, 85741x (1982).
Minacheva et al., Chemical Abstracts, vol. 100, No. 25, 220572m (Jun. 18, 1984).
JO 2028-134-A (Derwent 90-072990/10) to Chugai Pharmaceutical KK.
JO 2028-135-A (Derwent 90-072999/10) to Chugai Pharmaceutical KK.

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