Aminoalkyl-substituted azetidine platinum(II) complexes

Details Aminoalkyl-substituted azetidine platinum(II) complexes Aminoalkyl-substituted azetidine platinum(II) complexes

1988-01-08

1990-11-13

Rivers, Diana

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

548402, 548955, A61K 31555, C07F 1600

Patent

active

049703242

ABSTRACT:
Square-planar four-coordinate complexes of cis-platinum(II) with neutral bidentate aminoalkyl-substituted cycloalkylamine ligands and bromo-, chloro-, iodo-, nitrato-, oxalato-, or malanato-ligands possess antimicrobial activity as well as activity against transplanted L1210 and P388 murine leukemia cell lines.

REFERENCES:
patent: 4410544 (1983-10-01), Berg et al.
patent: 4584316 (1986-04-01), Rosenberg et al.
patent: 4661516 (1987-04-01), Brown et al.
patent: 4704464 (1987-11-01), Brunner et al.
patent: 4716157 (1987-12-01), Bitha et al.
patent: 4822892 (1989-04-01), Honda et al.
patent: 4902797 (1990-02-01), Totani et al.
Sosnovsky, et al., Chemical Abstracts, vol. 101(17):143678s (10/22/84).
Connors, et al., Chemical Abstracts, vol. 78: 79753q (1973).
Simon, et al., Rev. Roum. Biochim., vol. 14(2), pp. 117-125 (1977).
Tobe, et al., Chemical Abstracts, vol. 80: 55897e (1974).
Douple, et al., Chemical Abstracts, vol. 89: 157244t (1978).
Honda, et al., Chemical Abstracts, vol. 105: 97698f(1986).
Honda, et al., Chemical Abstracts, vol. 108: 106470s, 106471t (1988).
Inagaki et al., Inorganica Chim. Acta, 37:L547-L548 (1979).
Proc. of the Am. Assoc. of Cancer Res., Abstr. 652, p. 166, Hacker, et al.
Tanabe Seiyaku KK, Derwent Abstract 85-272741/44 of Japan 184,015, 09/19/85.
Chugai Pharmaceutical KK, Derwent Abstract 85-240374/39 of Japan 158,195, 08/19/85.
Tanabe Seiyaku KK (II), Derwent Abstract 84-131256/21 of Japan 67,262, 04/16/84.
Simon, et al., Chemical Abstracts, vol. 87, 145547q (1977).
Bystrenina, et al., Chemical Abstracts, vol. 96, 85741x (1982).
Minacheva, et al., Chemical Abstracts, vol. 100, No. 25, 220572m (6/18/84).

Affiliated with

Also associated with

Rating

Aminoalkyl-substituted azetidine platinum(II) complexes does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Aminoalkyl-substituted azetidine platinum(II) complexes, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Aminoalkyl-substituted azetidine platinum(II) complexes will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-777916