Aminoalkyl-indoles

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

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548504, 548507, 548426, 548427, C07D20918, C07D20920, C07D20910

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active

058696911

ABSTRACT:
The present invention provides novel tetrahydro-beta-carboline compounds having useful central nervous system activity. Further, there is provided tetrahydro-beta-carboline related compounds which are useful intermediates and have beneficial central nervous system activity. The invention provides formulations and methods for using the novel tetrahydro-beta-carboline and related compounds. Such compounds are particularly useful for the modulation of a 5-HT.sub.2B receptor.

REFERENCES:
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Derwent Abstract 84-115276/19 29.10.82 DE-3240-514-A.
Derwent Abstract 40991 14.4.67 US/3,840,637.
Dubois, et al., J. Org. Chem., 59, 434-441 (1994).
Legters, et al., Rccl. Trav. Chim. Pays-Bas, 111, 16-21 (1992).
Sato, K. And Kozikowski, A. P., Tetrahedron Letters, 30:31., 4073-4076, (1989).
Shima, et al., Chem. Pharm. Bull., 38:2, 564-566 (1990).

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