Aminoalkyl-derivatives of hydroxyalkyl-celluloses

Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives

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536 43, 536 44, 536 56, 536 90, 536 91, 536 96, 536100, C08B 1102, C08B 11145, C08B 11193, C08B 1120

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active

050048082

ABSTRACT:
A product comprising a water soluble, high molecular weight aminoalkyl-derivative of hydroxyalkyl-cellulose. The molecular weight of said cellulose is at least 50,000 daltons. One of the methods to obtain the product comprises reacting a hydroxyalkyl cellulose in a basic aqueous medium, in the presence of halogenalkylaminohalide compounds, to obtain a hydroxyalkyl cellulose having an alkylamino group which can be used as such or further reacted in the presence of an amide reducing agent, for instance sodium cyanoborohydride and a carbohydrate residue selected from the group consisting of mono-, di-, oligo-saccharides and starch.

REFERENCES:
Rowland et al., "The Relative Reactivities of the Hydroxyl Groups of Cotton Cellulose-A Progress Report", Textile Research Journal, vol. 37, No. 12, (Dec. 1967), pp. 1020-1030.
Guthrie et al., "Ion Exchange Celluloses for Chromatographic Separations", Industrial and Engineering Chemistry, vol. 52, p. 935, (Nov. 1960).
Morrison and Boyd, "Reactions of Cellulose", Organic Chemistry, 3rd Edition, pp. 1127-1128 (1978).

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