Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Patent
1992-12-01
1994-03-22
Shah, Mukund J.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
5142305, 544 6, 544 52, 544 70, 544105, A61K 31535, A61K 3154, C07D26536, C07D27916
Patent
active
052964779
ABSTRACT:
Compounds of general formula (I): ##STR1## wherein R.sub.1, R.sub.2, R.sub.3, n, X and A are defined in the description.
Medicinal products containing the same are useful as antidepressives or anxiolytics due to their 5-HT1A receptor agonist activity.
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Life Sciences 49, p. 37; "Use of a Conflict Procedure in Pigeons to Characterize Anxiolytic Drug Activity: Evaluation of Activity", etc. (1991), Koek et al.
"The Pharmacological Basis of Therapeutics" by Goodman and Gilman, Eighth Edition (1990) p. 429.
J. Med. Chem. 30, 1166.sub.]1176 (1987), Weinstock et al.
Acta Ther. 13(2), 125-129 (1987), Brunet et al.
Il Farmaco 44(1), 77-88 (1989), Moussavi et al.
Adam Gerard
Caignard Daniel H.
Depreux Patrick
Guardiola Beatrice
Lesieur Isabelle
Adir et Compagnie
Datlow Philip J.
Hueschen Gordon W.
Shah Mukund J.
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