Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Patent
1995-03-21
1996-04-30
Ramsuer, Robert W.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
514212, 5142282, 514253, 514321, 514367, 540603, 544 587, 544135, 544368, 546198, 548165, A61K 31495, A61K 31535, C07D41702
Patent
active
055125697
ABSTRACT:
The invention relates to the compounds of formula (I): ##STR1## in which R.sub.1 and R.sup.2 are as defined in the description, the optical isomers thereof,
and an addition salt thereof with a pharmaceutically-acceptable acid or base, and medicinal product useful for treating a mammal afflicted with a disease associated with sigma receptors.
REFERENCES:
patent: 5268381 (1993-12-01), Taverne et al.
Kaiser et al., Neurotransmissions, VII 1991, pp. 1-4.
Martindale, The Extra Pharmacopia, 30th Edition, pp. 567-568.
Z. Moussavi et al., Farmaco, Edizione Pratica, 44 (1) 1989, pp. 77-88.
J. Lowe et al., Journal of Medicinal Chemistry, "1-Naphthylpiperazine Derivatives As Potential Atyptical Antipsychotic Agents", 34 (6) 1991, pp. 1860-1866.
Adam Geard
Caignard Daniel-Henri
Depreux Patrick
Houssin Raymond
Lesieur Isabelle
Adir et Compagnie
Hueschen Gordon W.
Ramsuer Robert W.
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