Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1992-09-16
1993-12-07
Shah, Mukund J.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514373, 514375, 548159, 548165, 548172, 548173, 548221, 544 52, 544105, A61K 3142, A61K 31425, C07D27768, C07D41712
Patent
active
052683818
ABSTRACT:
Compounds of general formula (I): ##STR1## wherein R.sub.1, R.sub.2, R.sub.3, n, X and A are defined in the description. Medicinal products containing the same are useful as antidepressives or anxiolytics due to their 5-HT1A receptor agonist activity.
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Life Sciences 49, p. 37; "Use of a Conflict Procedure in Pigeons to Characterize Anxiolytic Drug Activity: Evaluation of Activity", etc., (1991), Koek et al.
"The Pharmacological Basis of Therapeutics" by Goodman and Gilman, Eighth Edition (1990) p. 49.
J. Med. Chem. 30, 1166-1176 (1987), Weinstock et al.
Acta Ther. 13(2), 125-129 (1987), Brunet et al.
Il Farmaco 44(1), 77-88 (1989), Moussavi et al.
Adam Gerard
Caignard Daniel H.
Depreux Patrick
Guardiola Beatrice
Lesieur Isabelle
Adir et Compagnie
Datlow Philip
Hueschen Gordon W.
Shah Mukund J.
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