Aminoalkoxy derivatives of propranolol for immunoassay applicati

Details Aminoalkoxy derivatives of propranolol for immunoassay applicati Aminoalkoxy derivatives of propranolol for immunoassay applicati

1982-04-15

1987-03-24

Hines, Robert V.

Organic compounds -- part of the class 532-570 series

Organic compounds

Amino nitrogen containing

26050118, 562451, 562467, 424 85, 436545, C07C 9306

Patent

active

046526811

ABSTRACT:
Derivatives of propranolol which have the following structure: ##STR1## where R is X--(CH.sub.2).sub.n --O, X is NH.sub.2 or COOH, n is 1,2,3,4, or 5, provided that when n is 1, X must be COOH, and R is attached in the 4', 5', 6', 7' or 8' position. The compounds are useful in immunoassay applications to (1) conjugate to a protein carrier in order to prepare antibodies to propranolol and (2) to conjugate to a tracer moiety such as a radiolabeled ligand, an enzyme, an enzyme substrate or a fluorescent dye.

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