Aminoalkanesulfonic acid derivatives and pharmaceutical composit

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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514428, 548556, 548570, 562104, 562105, 562106, 562107, C07C30915, A61K 31185

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active

054300525

ABSTRACT:
The present invention relates to a pharmaceutical composition for use in preventing or treating heart diseases in a mammal, which comprises at least one aminoalkanesulfonic acid derivative of the formula (I): ##STR1## wherein X is hydrogen or an amino acid residue; Y is hydrogen, a phenyl group or an alkyl group, which may have a hydroxy, amino, carboxy, phenyl or hydroxyphenyl group; or X and Y are joined to form a trimethylene or hydroxytrimethylene group; and at least one of X and Y is other than hydrogen;
or pharmaceutically acceptable salt thereof.

REFERENCES:
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Ienaga, et al., Chem. Pharm. Bull., 36 (1) 70-77 (1988).
Ienaga, et al., Chem. Pharm. Bull., 36(8) 2796-2801 (1988).
Higashiura, et al., J. Chem Soc. Perkin Trans. 1 (1989) pp. 1479-1481.
Chem. Abs. 101 (7): 54561f (1984).
Takeuchi Comp Biochem Physiol. C 56 63 (1977).
Schwenkkraus Arch Pharm (Weinheim) 323 93 (1990).

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