Aminoalcohol derivatives

Details Aminoalcohol derivatives Aminoalcohol derivatives

2011-04-19

2011-04-19

Andres, Janet L (Department: 1625)

Organic compounds -- part of the class 532-570 series

Organic compounds

Amino nitrogen containing

C546S304000, C546S335000

Reexamination Certificate

active

07928264

ABSTRACT:
The present invention relates to a compound of the formula [I]: wherein (a), in which —Y—, R4, R5and R6are4R5each as defined in the description, etc., R1is hydrogen, halogen, lower alkyl, hydroxy, etc., R2is hydrogen, lower alkyl or hydroxy(lower)alkyl, R3is hydrogen or an amino protective group,20R7is hydrogen, lower alkyl, cyclo(lower)alkyl, lower R9 alkenyl, —Z—R9or (b), in which —Z— is —0—, —S—, R9—SO— or —SO2—, and each R9is independently hydrogen, lower alkyl, cyclo(lower)alkyl, etc., and R8is -D-E-R10, in which -D- is —CONHSO2— or —S02NHCO—, E is bond or lower alkylene, and R10is halogen, cyano, carboxy, etc., or a prodrug thereof or a salt thereof. The compound [I] of the present invention and pharmaceutically acceptable salts thereof are useful for the prophylactic and/or the therapeutic treatment of ulcer, overactive bladder, and the like.

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